b'INNOVATIVE RESEARCHERSThe Pediatric Cancer Research Foundation supported these imaginative and far-sighted scientists whose findings set the stage for future advances in care:Susann Brady-Kalnay, PhDKyle MacQuarrie, MD, PhD Case Western Reserve University HospitalAnn & Robert H. Lurie Childrens Hospital of ChicagoUse of magnetic resonance fingerprinting for determining response toChemotherapy resistance and nuclear organization in rhabdomyosarcoma immunotherapy in pediatric brain tumors Mitchell Cairo, MD Theodore Moore, MD New York Medical College, Marie Fareri Childrens HospitalUCLA Mattel Childrens HospitalCancer genetics, tumor immunology and targeted treatments for childhood Phase I/II therapeutic research trials and development of new treatment and adolescent hematological malignancies and solid tumorsmodality for incurable brain tumorsBrian Crompton, MDAshley Plant-Fox, MD Dana-Farber Cancer InstituteAnn & Robert H. Lurie Childrens Hospital of Chicago Prospective validation of a prognostic liquid biopsy approach for pediatric Combination immunotherapy for diffuse intrinsic pontine glioma (DIPG)Ewing sarcomaChristinePratilas, MD Anat Epstein, MD, PhD Johns Hopkins School of Medicine Childrens Hospital Los Angeles Targeting SHP2 as a therapeutic strategy in fusion-negative Preclinical study to translate therapy using DNA hypomethylating agents forrhabdomyosarcomapediatric high grade gliomasKathleen Sakamoto, MD, PhD Silpa Gampala, PhD Lucile Packard Childrens Hospital Stanford Indiana University Exploration of mitochondrial pathway targeting for treatment of pediatric Decoding metabolic dependencies of MPNSTs and its microenvironment acute myeloid leukemia (AML) Zhaohui Gu, PhD Surojit Sarkar, PhD City of Hope Seattle Childrens Research Institute Single-cell Dissecting of High-risk B-cell Acute Lymphoblastic Leukemia Design of self-driving CAR T cell immunotherapies for metastatic solid tumors Rintaro Hashizume, MD, PhD Elliot Stieglitz, MD University of Alabama at Birmingham University of California, San Francisco Benioff Childrens Hospital Intranasal delivery of targeting nanoliposomal therapeutics for pediatric Innovative tests to determine treatment responsiveness for juvenile glioma myelomonocytic leukemia (JMML) Alex Kentsis, MD, PhDMasataka Suzuki, PhD Memorial Sloan-Kettering Cancer CenterBaylor College of MedicineCurative epigenetic therapies of refractory pediatric sarcomasImmunotherapy and CAR NK cell therapy for pediatric sarcomas Angela Liou, MDLeo Wang, MD, PhD Childrens Hospital of Philadelphia City of HopeElucidated how NF1 loss cooperates with SETD2 to drive pediatric high-gradeExploration of the signaling and activation of T cells expanded in glioma formation immunotherapyJohn Ligon, MD University of Florida Investigation of the immune response to RNA-nanoparticle vaccines anduse of these vaccines in combination with immune checkpoint inhibitorsfor metastatic osteosarcoma 11'